Oxford University, Structural Bioinformatics & Computational Biochemistry Unit
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Lukas Stelzl

Structural Bioinformatics and Computational Biochemistry Unit
Dept. of Biochemistry
University of Oxford
South Parks Road
Oxford
OX1 3QU
U.K.

Telephone: 01865 613304
Fax: 01865 613238

e-mail: lukas.stelzl@bioch.ox.ac.uk
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Background

I have read Biochemistry at Trinity College, Oxford between October 2006 and June 2010. My final year undergraduate research project project was supervised by Professor Christina Redfield. I investigated the structure and dynamics of the reductant transfering N-terminal domain of DsbD by NMR. I have employed Residual Dipolar Coupling (RDC) measurements and spin relaxation experiments to study protein structure and dynamics.

I have started my DPhil in Biochemistry in October 2010, moving to St Catherine`s College , Oxford . My doctoral work in the Departement of Biochemistry is jointly supervised by Professor Christina Redfield and Professor Mark Sansom of the Structural Bioinformatics and Computational Biochemistry Unit. I am funded by the BBSRC.

Research

Eventhough exchange between different structures of proteins underlie many biochemical processes, the mechanisms of conformational changes are still poorly understood. I am currently using NMR experiments and Molecular Dynamics simulations to study protein conformational changes in atomistic detail.

Publications
  • Despoina A. I. Mavridou, Lukas S. Stelzl, Stuart J. Ferguson and Christina Redfield
    1H, 13C and 15N resonance assignments for the oxidized and reduced states of the N-terminal domain of DsbD from Escherichia coli Biomol. NMR Assignments (2011) 1-5
    • Last updated 28 Feb 2012